Bruker BioSpin Launches Two New Versatile NMR Probes for Enhanced Flexibility and Sensitivity: QCI CryoProbe™ and BBFOplus SmartProbe™

The new QCI CryoProbe, a proton-optimized quadruple resonance NMR ‘inverse’ probe, increases sensitivity by about 300% on 1H and 13C compared to a room temperature probe. This new, versatile probe features four fully independent channels that enable simultaneous decoupling on multiple nuclei such as 13C, 31P and 15N.  This cost-efficient adaptability eliminates the need to change probes and makes this probe ideally suited for the study of RNA or DNA, and also allows all research on proteins, small molecules and metabolomics samples. Several recent discoveries in RNA research make this probe a very timely introduction for cutting-edge NMR research in RNA/DNA.

 

The SmartProbe technology enables fluorine observe with proton decoupling, or vice versa, which is  ideal for small molecule pharmaceutical research.  Together with Bruker’s ATM (automatic tune & match) rf technology, the BBFOplus SmartProbe allows for fully automatic nucleus switching, thereby increasing throughput and delivering optimum performance from sample to sample. The BBFOplus SmartProbe has evolved from the well-proven BBFO product line introduced by Bruker in 2007, which successfully combined the individual benefits of the highly successful broadband inverse and broadband observe NMR probe ranges, and yields the optimum high performance NMR probe solution with maximum flexibility and throughput.