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- MR Newsletter 08/2011
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HyStar/Compass Software
Software for Hyphenated Experiments
HyStar™ coordinates experiments when a liquid chromatography system is coupled with spectroscopic methods like NMR or MS. HyStar controls the chromatography system instruments, which interface in diverting the solvent flow into the spectrometers or intermediate collectors.
The HyStar concept is an open concept that can be used for many types of experiments. At a basic level it can be used to control a chromatography system and, in a more complex setup, an LC-MS system. In an LC/MS-SPE-NMR setup, HyStar triggers sample collection in solid phase extraction cartridges, based on chromatograms reconstructed from MS data. The sample is then transferred into a flow NMR probe and the measurement of the NMR spectra initiated.
Systems controlled by HyStar
- Agilent (most 1100/1200 series instruments).
- Waters (AQUITY™ UPLC, Alliance 2695, 2795 etc.).
- Hitachi (LaChrom Elite® HPLC System).
- Dionex (UltiMate 3000 Capillary/Nano LC system).
- Liquid handlers (as autosampler and/or fraction collector).
- CTC (HTS Pal autosampler).
MS and NMR spectrometers:
- Bruker Avance NMR spectrometers.
- Bruker Daltonics esquire/HCT ESI-Ion Trap.
- FTMS and Qh-FTMS (Fourier Transform Mass Spectrometers).
- micrOTOF/MicrOTOF-Q Time-of-Flight mass spectrometers.
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