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Small Animal MRI at Ultra-High Fields of 11.7 T
BioSpec 117/16 USR
- BioSpec 117/16 USR
Bruker BioSpin MRI has extended its well-proven BioSpec® series with an 11.7 T Ultra Shielded Refrigerated (USR) system. This is a new milestone in routine MRI because for the first time an actively shielded magnet is available with a horizontal MRI system at this high field strength.
Features
- Ultra high field of 11.7 T with unsurpassed signal-to-noise ratio
- USR magnets with two-year service intervals
- Helium zero-boil-off and Nitrogen free magnet technology
- 72 mm free access for imaging of rats and mice
- Integrated gradient and shim systems with the highest slew rates, gradient strengths and outstanding duty cycle performance with the BGA-S to overcome high field challenges
- Scalable Avance™ III architecture for multiple receiver and transmitter channel configuration
- Phased array coil technology for parallel imaging
- IntraGate for self-gated cardiac imaging without external triggering devices
- AutoPacTM - Motorized and software controlled animal positioning system
- Routine user interface ParaVision with state-of-the-art MR animal imaging techniques
Technical description
- Turbo Spin Echo (RARE) with 68 x 68 µm2 in plane resolution, 0.5 mm slice thickness.
High Resolution Neuroanatomy
The BioSpec 117/16 USR system enables highly resolved routine imaging of the rat brain leading to outstanding image quality. The signal-to-noise ratio obtained at this field strength allows one to acquire high resolution images of the very tiny in the brain!
- Diffusion Tensor Imaging (DTI) on a rat brain at 11.7T
Diffusion Tensor Imaging
Diffusion Tensor Imaging (DTI) benefits tremendously from the high signal-to-noise ratio that is achieved by the 11.7 T. Images taken in 14 minutes using a EPI-SE sequence: The color coded Eigenvalue image displays the main principle diffusion directions after evaluating 30 different diffusion directions. Diffusion encoding: red: left-right; green: topbottom; blue: in-out.
- High resolution fMRI at 11.7 T
fMRI
High resolution fMRI at 11.7 T demonstrating the increased BOLD sensitivity at higher magnetic fields (in plane resolution of 75 x 75 µm²).
Courtesy: M. Hoehn, MPI, Cologne