AVANCE III

Fastest, Highest Performance and Most Flexible NMR Spectrometer on the Market

The ultimate NMR platform for life-science and materials research, as well as a robust, automated, easy-to-use NMR analysis system for pharma/biotech, chemistry, metabolomics, nutritional science and molecular diagnostics research.

With the further enhanced AVANCE III NMR spectrometer architecture, we introduce the fastest, highest performing and most flexible NMR spectrometer on the market. The Avance III architecture is based on a forward-thinking electronics concept that delivers an unprecedented level of digital control, speed, flexibility and exceptionally pure NMR frequency generation.

The AVANCE III is the next generation in the very successful AVANCE series product line, which has established Bruker BioSpin as the clear global technology and market leader in NMR and pre-clinical MRI. The AVANCE III spectrometer is designed around an advanced digital concept that provides an optimized pathway for highest speed RF generation and data acquisition with a highly modular and scalable transmitter and receiver channel architecture.

Next-generation digital lock:
DigiLock™ The DigiLock is now designed with an entirely new ‘Direct RF’ concept, which eliminates the need for analog mixers.

Improved NMR stability monitoring sample temperature
A novel and modular high performance variable temperature system consisting of SmartVT™ - interface for NMR sample temperature control - and SmartCooler™, both leading to significantly improved NMR stability.

Improved immunity to external RF disturbances
New multi-purpose highest performance High Power Low Noise Preamplifier (HPLNA) with enhanced noise figures and improved immunity to external RF perturbations.

Flexible Communication Structure

The Avance III communication backbone consists of two data paths: a LAN-based approach (ethernet) for non-time critical applications (diagnostics, firmware upgrades, configuration parameters) and an ultra-fast LVDS bus for timecritical (real-time) applications.

Advanced RF Generation

Bruker’s patented digital RF generation provides the most precise and stable RF pulses, greatly surpassing any commercially available technologies for the highest spectral purity. In addition to the highest available phase and frequency resolution, RF parameters can be switched in only 25 ns, including simultaneous phase, frequency and amplitude switching.

Unparalleled Dynamic Range

The 2nd Generation Digital Receiver enables the highest dynamic range and digital resolution, thanks to the use of a special ADC architecture, leading to over 22 usable bits.

Beyond the Electronics

Together with a wealth of performance-leading solids and liquids probes, industry leading TopSpin operating software and a broad array of automation and hyphenation options, the Avance III is the NMR spectrometer that will enable not just the latest, but also future experiments and research
applications.